Farnesoid X receptor: from structure to potential clinical applications

J Med Chem. 2005 Aug 25;48(17):5383-403. doi: 10.1021/jm0582221.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Bile Acids and Salts / chemical synthesis
  • Bile Acids and Salts / chemistry
  • Bile Acids and Salts / metabolism
  • Binding Sites
  • Cardiovascular Diseases / metabolism
  • DNA-Binding Proteins / chemistry*
  • DNA-Binding Proteins / drug effects*
  • DNA-Binding Proteins / metabolism
  • Diabetes Mellitus, Type 2 / metabolism
  • Humans
  • Insulin Resistance
  • Ligands
  • Models, Molecular
  • Protein Structure, Tertiary
  • Receptors, Cytoplasmic and Nuclear / chemistry*
  • Receptors, Cytoplasmic and Nuclear / drug effects*
  • Receptors, Cytoplasmic and Nuclear / metabolism
  • Transcription Factors / chemistry*
  • Transcription Factors / drug effects*
  • Transcription Factors / metabolism

Substances

  • Bile Acids and Salts
  • DNA-Binding Proteins
  • Ligands
  • Receptors, Cytoplasmic and Nuclear
  • Transcription Factors
  • farnesoid X-activated receptor